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June 27, 2026

Association Between Ankylosing Spondylitis and Periodontitis: A Systematic Review.

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Authors

VQValentin QuemardZPZocko Ange Désiré PockpaCVChristian Verner

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Overview

Systematic review investigates the link between ankylosing spondylitis and periodontitis, suggesting potential implications for treatment.

Key Points

  • This review aims to explore the relationship between ankylosing spondylitis and periodontitis, two chronic inflammatory conditions.
  • Conducted searches in PubMed, The Cochrane Library, Scopus, and Web of Science following PRISMA 2020 guidelines.
  • Selected 18 eligible studies (3 cohort, 14 case-control, 1 Mendelian randomisation) and assessed their quality using SIGN and STROBE-MR methodologies.
  • Analyzed various parameters like bleeding on probing, probing pocket depth, clinical attachment loss, and inflammatory markers.
  • Results showed inconsistent prevalence of periodontitis in ankylosing spondylitis patients, with some correlations to inflammatory markers.
  • Treatment with anti-TNF-α agents linked to decreased probing pocket depth and clinical attachment loss.
  • Periodontal disease may elevate inflammatory markers (IL-6, TNF-α, CRP, ESR) in ankylosing spondylitis patients.

Cite This Study

Quemard et al. (2026) studied this question.

synapsesocial.com/papers/6a3f6922aea7db3c19540109https://doi.org/10.3290/j.ohpd.c_2747
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Also Consider

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  1. 1Psoriasis, Psoriatic Arthritis, and Periodontitis: An Umbrella Review of Current Evidence v12025
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  5. 5The Impact of Periodontal Therapy on Disease Activity in Patients with Rheumatoid Arthritis and Concomitant Periodontitis: A Systematic Review and Meta-Analysis2026 · 1 citations