Key result
The twin-ribozyme intron (Dir.S956-1) demonstrated site-specific RNA-based targeting into its natural SSU rRNA site in vitro, in E. coli, and in yeast.
Reverse splicing provides a site-specific RNA-based targeting mechanism for group I intron spread into homologous sites, in addition to endonuclease-mediated homing.
No takes yet. Share an insight, caveat, or question.
Reverse splicing may enable RNA-based intron mobility; leaves open its role versus endonuclease homing in nature.
Åsa Birna Birgisdottir (2005) studied this question. twin-ribozyme intron (Dir.S956-1) was evaluated on Site-specific RNA-based targeting into SSU rRNA site. The twin-ribozyme intron (Dir.S956-1) demonstrated site-specific RNA-based targeting into its natural SSU rRNA site in vitro, in E. coli, and in yeast.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: