Key result
Type 1 diabetes mellitus was associated with an increased risk of myocardial infarction (HR 3.26; 95% CI 2.47-4.30), heart failure, and ischemic stroke.
Why the study?
Do Type 1 and Type 2 diabetes mellitus increase the incidence of specific cardiovascular diseases in adults?
Population
71,483 Swedish adults from two population-based prospective cohorts
Comparison
Type 1 diabetes mellitus and Type 2 diabetes… vs Adults without diabetes mellitus
Design
Cohort
Authors
Loading...
T1DM linked to elevated MI risk; leaves open whether intensified prevention improves outcomes in this population.
Cohort (n=71,483)
Yes
Do Type 1 and Type 2 diabetes mellitus increase the incidence of specific cardiovascular diseases in adults?
Hazard Ratio: 3.26 (95% CI 2.47–4.3)
Both Type 1 and Type 2 diabetes mellitus are associated with an increased risk of major cardiovascular outcomes, with Type 2 diabetes also showing associations with aortic valve stenosis, atrial fibrillation (long-term), and a lower risk of abdominal aortic aneurysm and intracerebral hemorrhage.
Larsson et al. (2018) conducted a cohort in Type 1 and type 2 diabetes mellitus (n=71,483). Type 1 and type 2 diabetes mellitus vs. Individuals without diabetes was evaluated on Myocardial infarction (HR 3.26, 95% CI 2.47-4.30). Type 1 diabetes mellitus was associated with an increased risk of myocardial infarction (HR 3.26; 95% CI 2.47-4.30), heart failure, and ischemic stroke.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: