Key result
An oral anticoagulation self-management program increased time in therapeutic range from 53.6% to 57.1% (p=0.30) and reduced the proportion of patients with INR >5 from 3.9% to 2.0% (p=0.04).
Why the study?
To analyze the impact of implementing an oral anticoagulation self-monitoring and self-management program among patients with a mechanical valve prosthesis.
Does an oral anticoagulation self-monitoring and self-management program improve time in therapeutic range and reduce complications in patients with mechanical heart valve prosthesis?
Observational (n=44)
No
Does an oral anticoagulation self-monitoring and self-management program improve time in therapeutic range and reduce complications in patients with mechanical heart valve prosthesis?
Absolute Event Rate: 57.1% vs 53.6%
p-value: p=0.30
An oral anticoagulation self-monitoring program in patients with mechanical heart valves significantly reduced the proportion of patients with dangerously high INR levels (>5) without increasing bleeding or thromboembolic complications.
Self-monitoring was associated with fewer INR >5 events in mechanical valve patients; leaves open whether it improves TTR or outcomes in trials.
Objective: To analyze impact of implementation of an oral anticoagulation self-monitoring and self-management program among patients with mechanical valve prosthesis. Materials & methods: Observational and retrospective study performed in Hospital Moises Broggi, Barcelona, Spain. The program started on June 2019. The study compared 6-month period before and after the implementation of the program. Results: The study included 44 patients. There was a numerical increase of time in therapeutic range from 53.6 ± 21.3% to 57.1 ± 15.7% (p = 0.30). Proportion of patients with international normalized ratio (INR) >5 significantly decreased from 3.9 to 2.0% (p = 0.04). No significant differences were observed in thromboembolic or bleeding complications. Visits to emergency department decreased from (29.5 to 22.7%; p = 0.41). Conclusion: Oral anticoagulation self-monitoring and self-management program seems an appropriate approach that could provide additional benefits in selected patients with mechanical valve prosthesis.
No takes yet. Share an insight, caveat, or question.
Blanch et al. (2021) conducted an observational in mechanical heart valve prosthesis (n=44). Oral anticoagulation self-monitoring and self-management program vs. 6-month period before implementation was evaluated on Time in therapeutic range (p=0.30). An oral anticoagulation self-management program increased time in therapeutic range from 53.6% to 57.1% (p=0.30) and reduced the proportion of patients with INR >5 from 3.9% to 2.0% (p=0.04).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: