Key result
At 3 months after cobalt-chromium everolimus-eluting stent implantation, STEMI lesions had a higher median percentage of uncovered struts compared to stable CAD lesions (5.5% vs. 1.6%, P<0.001).
Why the study?
Early local vascular healing after drug-eluting stent implantation in STEMI lesions, which mainly concerns stent thrombosis, remains unclear.
Does early local vascular healing at 3 months differ after everolimus-eluting cobalt-chromium stent implantation in patients with STEMI compared to stable CAD?
Cohort (n=96)
Yes
Does early local vascular healing at 3 months differ after everolimus-eluting cobalt-chromium stent implantation in patients with STEMI compared to stable CAD?
Absolute Event Rate: 5.5% vs 1.6%
p-value: p=<0.001
Early vascular healing and strut coverage at 3 months after everolimus-eluting stent implantation is slightly delayed in STEMI compared to stable CAD, but remains clinically acceptable.
BACKGROUND: Second-generation drug-eluting stents (DES) reduce the incidence of stent thrombosis, even in patients with ST-segment elevated myocardial infarction (STEMI). However, the early local vascular healing after DES implantation in STEMI lesions, which mainly concerns stent thrombosis, is still unclear. METHODS AND RESULTS: ; P=0.009]. CONCLUSIONS: Although strut coverage after CoCr-EES implantation for STEMI lesions was slightly delayed, the healing process appeared to be acceptable in both STEMI and stable CAD.
No takes yet. Share an insight, caveat, or question.
Ishida et al. (2020) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) and stable coronary artery disease (CAD) (n=96). ST-segment elevation myocardial infarction (STEMI) vs. Stable coronary artery disease (CAD) was evaluated on Incidence of uncovered struts at the 3-month follow-up (p=<0.001). At 3 months after cobalt-chromium everolimus-eluting stent implantation, STEMI lesions had a higher median percentage of uncovered struts compared to stable CAD lesions (5.5% vs. 1.6%, P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: