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December 2, 2015Prenatal Diagnosis

Utility of novel fetal echocardiographic morphometric measures of the aortic arch in the diagnosis of neonatal coarctation of the aorta

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Authors

BABhawna AryaSeattle Children's HospitalABAarti BhatSeattle Children's HospitalMVMargaret M. VernonBoston Children's Hospital

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Implication

Retrospective review identifies novel echocardiographic measures to enhance prenatal CoA diagnosis in neonates, indicating potential clinical benefits.

Key Points

  • This research aims to improve the prenatal diagnosis of neonatal coarctation of the aorta (CoA) through novel echocardiographic measures.
  • Retrospective review of fetal echocardiograms conducted from 2007 to 2014 for prenatal suspicion of CoA.
  • Evaluation of right/left ventricular dimensions and aortic measurements including LCSA, AAo-DAo angle, and TAo-DAo angle prior to delivery.
  • Postnatal follow-up included diagnosis and surgical outcomes.
  • Subjects with CoA exhibited significant differences in LCSA, AAo-DAo angle, and TAo-DAo angle compared to those without (p < 0.0001).
  • An LCSA >4.5 mm showed 80% sensitivity and 95% specificity, AAo-DAo angle ≤20.31° demonstrated 95% sensitivity and 100% specificity, and TAo-DAo angle ≥96.15° indicated 90% sensitivity and 100% specificity for identifying CoA.

Cite This Study

Arya et al. (2015) studied this question.

synapsesocial.com/papers/6a3fd68a901a52dbcb71b0f8https://doi.org/10.1002/pd.4753
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