Key result
Increasing age is strongly linked to reduced aortic distensibility in healthy volunteers.
Why the study?
Non-invasive assessment of aortic mechanical properties may be useful for early atheroma detection, requiring evaluation of available echocardiographic indices.
Can 2D echocardiographic assessment of aortic distensibility detect age-related changes in aortic mechanical properties in healthy volunteers?
Population
49 healthy non-smoking volunteers
Comparison
Echo-Doppler indices of aortic stiffness across age
Design
Cross-sectional study
Authors
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Supports age-adjusted aortic distensibility norms in imaging; leaves open clinical utility and outcomes in disease.
Cross-Sectional (n=49)
Can 2D echocardiographic assessment of aortic distensibility detect age-related changes in aortic mechanical properties in healthy volunteers?
Effect estimate: r = 0.69 (Ep elastic modulus), r = 0.65 (Beta index)
2D echocardiographic assessment of aortic distensibility, specifically Ep elastic modulus and Beta index, can sensitively detect age-related reductions in aortic mechanical properties even in healthy individuals.
Lacombe et al. (1992) conducted a cross-sectional in Healthy (n=49). Increasing age was evaluated on Age-related changes in aortic distensibility (Ep elastic modulus and Beta index) (r = 0.69 (Ep elastic modulus), r = 0.65 (Beta index)). Increasing age was significantly associated with reduced aortic distensibility in healthy volunteers, measured by Ep elastic modulus (r=0.69) and Beta index (r=0.65).
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