Key result
Physiological ageing was associated with a progressive impairment of the elastic properties of the aortic wall, including decreased distensibility and increased pulse wave velocity (P<0.001).
Population
85 healthy subjects free of overt cardiovascular disease, subdivided into 6 classes of age
Design
Cross-sectional
Authors
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Offers CMR reference values for aortic stiffness in healthy aging; leaves open prognostic validation in longitudinal cohorts.
Observational (n=85)
p-value: p=<0.001
Physiological aging is associated with progressive impairment of aortic wall elastic properties as measured by CMR, providing reference values for healthy subjects.
Aquaro et al. (2013) conducted an observational in Healthy subjects (n=85). Cardiac magnetic resonance (CMR) was evaluated on Age-dependent changes in distensibility, maximum rate of systolic distension (MRSD), and pulse wave velocity (PWV) (p=<0.001). Physiological ageing was associated with a progressive impairment of the elastic properties of the aortic wall, including decreased distensibility and increased pulse wave velocity (P<0.001).
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