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June 28, 2026Anaesthesia

One‐lung ventilation and positive end‐expiratory pressure titration: a reply

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Authors

WWWei WangJWJingxiang Wu

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Overview

Pragmatic trial evaluates PEEP titration approach in thoracic anaesthesia, indicating targeted strategies could enhance outcomes.

Key Points

  • This trial aims to evaluate the effectiveness of a pragmatic electrical impedance tomography approach for determining PEEP during one-lung ventilation.
  • Employs electrical impedance tomography to set a patient-specific PEEP before surgical incision.
  • Maintains selected PEEP during one-lung ventilation.
  • Discusses practical limitations of continuous intra-operative monitoring.
  • Electrical impedance tomography-guided PEEP levels were generally higher than routine practice.
  • Conventional fixed PEEP remained adequate for older patients with preserved lung function.
  • Increased PEEP may not improve outcomes within a safe range; targeted approaches may benefit high-risk patient populations.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6a40b9c461bb0a67205c5d7ahttps://doi.org/10.1111/anae.70276
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  1. 1The search for the missing link between better physiology and patient outcomes: a reply2026
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