Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 28, 2026MedCommOpen Access

The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity

View Full Paper
Ask AI
Bookmark
Share

Authors

AFAnni FengQLQi LiNJNing Jiang

Discussion

Loading...

Member takes

Overview

This review examines the dual roles of regulatory B cells in infections and cancer, indicating their complex regulatory functions in immunity.

Key Points

  • The aim is to explore the dual roles of regulatory B cells in immune regulation across various clinical contexts.
  • Review of literature on regulatory B cells in infections, cancer, autoimmune disorders, and transplantation.
  • Analysis of cytokines and pathways involved in Bregs function.
  • Discussion of therapeutic potential in modulating Bregs activities.
  • Regulatory B cells protect against autoimmunity and promote transplant tolerance.
  • They can also enhance the progression of chronic infections and cancers by suppressing immune responses.
  • A functional dichotomy was identified, emphasizing the dual roles of Bregs in health and disease.

Cite This Study

Feng et al. (2026) studied this question.

synapsesocial.com/papers/6a40bae361bb0a67205c6901https://doi.org/10.1002/mco2.70850
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Regulatory B-cells: immunomodulating mechanisms and important cellular targets underlining immunotherapy by immunoregulation2024
  2. 2Regulatory B Cells in Tumor Microenvironment2026 · 2 citations
  3. 3Harnessing the Duality of Regulatory B Cells: From Identification of Characteristic Molecules to Therapeutic Targeting2026
  4. 4Regulatory B cells in the central nervous system: From immune regulation to neuroprotection2026
  5. 5The half-century odyssey of regulatory B cells: from Breg discovery to emerging frontiers2025 · 8 citations