Key result
Female patients with hypertension exhibited a significantly steeper increase in arterial elastance index at 75 W of exercise compared to males (0.69 vs 0.43, P=0.018).
Why the study?
Does female gender affect the arterial elastance index response to exercise in patients with hypertension compared to males?
Population
298 patients with hypertension (149 males; 149 females), mean age 59.
Comparison
Female gender vs Male gender
Design
Cross-sectional
Authors
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Hypothesis-generating for sex differences in exercise arterial elastance among hypertensives; prospective studies needed before clinical consideration.
Observational (n=298)
Does female gender affect the arterial elastance index response to exercise in patients with hypertension compared to males?
Absolute Event Rate: 0.69% vs 0.43%
p-value: p=0.018
Women with hypertension exhibit a steeper increase in dynamic arterial stiffness during exercise compared to men, which correlates with reduced exercise capacity and may contribute to the development of heart failure with preserved ejection fraction.
Park et al. (2008) conducted an observational in hypertension (n=298). Female gender vs. Male gender was evaluated on Magnitude of change in arterial elastance index at 75 W of exercise (p=0.018). Female patients with hypertension exhibited a significantly steeper increase in arterial elastance index at 75 W of exercise compared to males (0.69 vs 0.43, P=0.018).
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