Key result
Acute perimyocarditis was associated with a significantly reduced left ventricular twist angle compared to normal subjects (10.9° vs 17.6°, P<0.001).
Why the study?
Does speckle tracking echocardiography detect subclinical left ventricular dysfunction in patients with acute perimyocarditis compared to normal subjects?
Observational (n=58)
Does speckle tracking echocardiography detect subclinical left ventricular dysfunction in patients with acute perimyocarditis compared to normal subjects?
Speckle tracking echocardiography can detect subclinical left ventricular dysfunction, specifically reduced longitudinal strain and twist angle, in patients with acute perimyocarditis even when apparent LV function is normal.
Answers are grounded in this paper and cite their sources.
Speckle-tracking strain detects reduced LV function in acute perimyocarditis; leaves open its diagnostic utility pending validation studies.
BACKGROUND: Left ventricular (LV) function in acute perimyocarditis is variable. We evaluated LV function in patients with acute perimyocarditis with speckle tracking. METHODS: Thirty-eight patients with acute perimyocarditis and 20 normal subjects underwent echocardiographic examination. Three-layers strain and twist angle were assessed with a speckle tracking. Follow-up echo was available in 21 patients. RESULTS: Strain was higher in normal subjects than in patients with perimyocarditis. Twist angle was reduced in perimyocarditis--10.9° ± 5.4 versus 17.6° ± 5.8, P < 0.001. Longitudinal strain and twist angle were higher in normal subjects than in patients with perimyocarditis and apparently normal LV function. Follow-up echo in 21 patients revealed improvement in longitudinal strain. CONCLUSIONS: Patients with acute perimyocarditis have lower twist angle, longitudinal and circumferential strain. Patients with perimyocarditis and normal function have lower longitudinal strain and twist angle. Short-term follow-up demonstrated improvement in clinical parameters and longitudinal strain despite of residual regional LV dysfunction.
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Leitman et al. (2011) conducted an observational in Acute perimyocarditis (n=58). Acute perimyocarditis vs. Normal subjects was evaluated on Left ventricular twist angle (p=<0.001). Acute perimyocarditis was associated with a significantly reduced left ventricular twist angle compared to normal subjects (10.9° vs 17.6°, P<0.001).
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