Key result
Frailty affects ~90% of hospitalized HFpEF patients and bidirectionally accelerates heart failure progression.
Why the study?
Heart failure and frailty frequently coexist in older adults and are associated with poor clinical outcomes, warranting a synthesis of current evidence on their bidirectional relationship.
Design
Integrated review
Authors
Loading...
Supports integrating frailty assessment into HF care; leaves open validation of HF-specific tools and targeted interventions.
This review highlights the bidirectional relationship between frailty and heart failure, emphasizing the need for HF-specific frailty assessment tools and targeted management strategies.
Uchmanowicz et al. (2026) conducted a review in Heart failure and frailty. Frailty was evaluated. Frailty affects 15-76% of patients with chronic heart failure, approaching 90% in hospitalized HFpEF patients, and shares a bidirectional relationship where each condition accelerates the other.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: