What is the clinical evidence from this study?

Study design: Observational. Population: Coronary artery disease (n=920). Intervention: Age ≥ 85 years vs. Age < 85 years. Primary outcome: In-hospital mortality.

April 22, 2015Kardiologia PolskaOpen Access

In-hospital outcomes and mortality in octogenarians after percutaneous coronary intervention

Q: What are the key findings of this study?

Patients aged 85 years and older undergoing percutaneous coronary intervention experienced higher rates of in-hospital mortality (4.8% vs 0.83%) and contrast-induced nephropathy (18.2% vs 6.2%) compared to younger patients.

View Full Paper

Ask AI

Bookmark

Key result

Patients aged 85 years and older undergoing percutaneous coronary intervention experienced higher rates of in-hospital mortality (4.8% vs 0.83%) and contrast-induced nephropathy (18.2% vs 6.2%) compared to younger patients.

Why the study?

Does percutaneous coronary intervention in patients aged ≥85 years compared to younger patients result in higher rates of in-hospital complications?

Population

920 consecutive patients with coronary disease undergoing percutaneous coronary intervention. Divided into…

Comparison

Percutaneous coronary intervention in patients… vs Percutaneous coronary intervention in patients…

Design

Cohort

Follow-up

in-hospital

Authors

MRMonika Rynkowska‐Kidawa MZMarzenna Zielińska KCKrzysztof Chiżyński

Discussion

Member takes

Overview

PCI outcomes in patients ≥85 years warrant cautious application; leaves open questions on optimal strategies pending prospective data.

Study Design

Type

Observational (n=920)

Multicenter

Structured PICO

Does percutaneous coronary intervention in patients aged ≥85 years compared to younger patients result in higher rates of in-hospital complications?

Population

920 consecutive patients with stable coronary artery disease or acute coronary syndrome undergoing percutaneous coronary intervention, evaluated for in-hospital outcomes.

Exposure

Percutaneous coronary intervention (PCI) in patients aged ≥85 years

Comparator

Percutaneous coronary intervention (PCI) in patients aged <85 years

Outcome

In-hospital major adverse cardiovascular events (MACE), defined as a composite of death, myocardial infarction, and transient ischaemic attackcomposite

Main Result

Absolute Event Rate: 4.8% vs 0.83%

PCI in patients aged ≥85 years is associated with higher in-hospital mortality and contrast-induced nephropathy compared to younger patients, particularly in the setting of acute coronary syndrome.

Limitations

Single-centre study without randomisation
Observational and retrospective design
Analysis limited to in-hospital outcomes only
Small size of the ≥85 years study group
PCI procedure outcomes and complications were presented as age-unadjusted results
Single centre
Without randomisation
Observational and retrospective
In-hospital outcomes only
Small size of the GER study group
Age-unadjusted results

Cite This Study

Rynkowska‐Kidawa et al. (2015) conducted an observational in Coronary artery disease (n=920). Age ≥ 85 years vs. Age < 85 years was evaluated on In-hospital mortality. Patients aged 85 years and older undergoing percutaneous coronary intervention experienced higher rates of in-hospital mortality (4.8% vs 0.83%) and contrast-induced nephropathy (18.2% vs 6.2%) compared to younger patients.

synapsesocial.com/papers/6a428c47c97252f2d147be2e https://doi.org/10.5603/kp.a2014.0247

View Full Paper

Ask AI

Bookmark

April 22, 2015Kardiologia PolskaOpen Access

In-hospital outcomes and mortality in octogenarians after percutaneous coronary intervention

View Full Paper

Ask AI

Bookmark

Key result

Why the study?

Does percutaneous coronary intervention in patients aged ≥85 years compared to younger patients result in higher rates of in-hospital complications?

Population

920 consecutive patients with coronary disease undergoing percutaneous coronary intervention. Divided into…

Comparison

Percutaneous coronary intervention in patients… vs Percutaneous coronary intervention in patients…

Design

Cohort

Follow-up

in-hospital

Authors

MRMonika Rynkowska‐Kidawa MZMarzenna Zielińska KCKrzysztof Chiżyński

Discussion

Member takes

Overview

PCI outcomes in patients ≥85 years warrant cautious application; leaves open questions on optimal strategies pending prospective data.

Study Design

Type

Observational (n=920)

Multicenter

Structured PICO

Does percutaneous coronary intervention in patients aged ≥85 years compared to younger patients result in higher rates of in-hospital complications?

Population

920 consecutive patients with stable coronary artery disease or acute coronary syndrome undergoing percutaneous coronary intervention, evaluated for in-hospital outcomes.

Exposure

Percutaneous coronary intervention (PCI) in patients aged ≥85 years

Comparator

Percutaneous coronary intervention (PCI) in patients aged <85 years

Outcome

In-hospital major adverse cardiovascular events (MACE), defined as a composite of death, myocardial infarction, and transient ischaemic attackcomposite

Main Result

Absolute Event Rate: 4.8% vs 0.83%

PCI in patients aged ≥85 years is associated with higher in-hospital mortality and contrast-induced nephropathy compared to younger patients, particularly in the setting of acute coronary syndrome.

Limitations

Single-centre study without randomisation
Observational and retrospective design
Analysis limited to in-hospital outcomes only
Small size of the ≥85 years study group
PCI procedure outcomes and complications were presented as age-unadjusted results
Single centre
Without randomisation
Observational and retrospective
In-hospital outcomes only
Small size of the GER study group
Age-unadjusted results

Cite This Study

synapsesocial.com/papers/6a428c47c97252f2d147be2e https://doi.org/10.5603/kp.a2014.0247

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

View Full Paper

Ask AI

Bookmark