Key result
The authors review the benefits and risks of interventional versus medical management for chronic symptomatic coronary artery disease in patients aged 75 years or older based on the TIME trial results.
Why the study?
Does interventional management improve outcomes and quality of life compared to medical management in elderly patients ≥75 years with chronic symptomatic coronary artery disease?
Does interventional management improve outcomes and quality of life compared to medical management in elderly patients ≥75 years with chronic symptomatic coronary artery disease?
This review discusses the implications of the TIME trial regarding the benefits and risks of invasive versus medical management for chronic angina in patients aged 75 and older.
Answers are grounded in this paper and cite their sources.
Invasive strategy improves QoL and reduces events in elderly with refractory angina; extends revascularization benefit to patients >75 years.
Young patients with coronary artery disease usually benefit from revascularization in terms of symptom relief and outcome. There are no prospective data available, however, for patients older than age 75 years, for whom quality of life might be more of an issue than quantity of life and for whom risk profiles and comorbidities make treating physicians more reluctant to prescribe an invasive procedure. The recently published Trial of Invasive vs. Medical therapy in Elderly patients (TIME) was the first to address patients > or =75 years of age with chronic angina despite standard medical therapy. The authors discuss the benefits and risks of interventional vs. medical management of chronic, symptomatic coronary artery disease in elderly patients in view of the TIME results and their clinical implications.
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Kuster et al. (2004) conducted a review in Chronic symptomatic coronary artery disease. Interventional management vs. Medical management was evaluated. The authors review the benefits and risks of interventional versus medical management for chronic symptomatic coronary artery disease in patients aged 75 years or older based on the TIME trial results.
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