Ältere Patienten mit symptomatischer koronarer Herzkrankheit: Ist die interventionelle Behandlung eine reelle Option?

Q: What is the clinical evidence from this study?

Study design: RCT. Population: symptomatic coronary artery disease (n=301). Intervention: Invasive strategy (coronary angiography followed by CABG or PCI) vs. Optimised medical strategy. Primary outcome: Critical clinical events (p=<0.0001).

Q: What does this research mean for the field?

In elderly patients (≥75 years) with symptomatic coronary artery disease, an invasive revascularization strategy significantly reduces one-year critical clinical events compared to optimized medical therapy without increasing mortality risk or overall costs. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Matthias Pfisterer

doi:10.3390/cardiovascmed6010003

January 31, 2003Cardiovascular MedicineOpen Access

Ältere Patienten mit symptomatischer koronarer Herzkrankheit: Ist die interventionelle Behandlung eine reelle Option?

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Why the study?

The benefit and cost-effectiveness of invasive versus medical treatment in symptomatic coronary artery disease patients aged 75 years or older was uncertain.

Study Design

Type

RCT (n=301)

PICO

P

Population

301 symptomatic patients with coronary artery disease aged ≥75 years, followed for one year.

I

Intervention / Comparator

Invasive strategy (coronary angiography followed by CABG or PCI) vs Optimised medical strategy

O

Primary Outcome

Critical clinical events, p=<0.0001

Main Result

Absolute Event Rate: 29% vs 79%

p-value: p=<0.0001

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Cite This Study

Matthias Pfisterer (2003) conducted an RCT in symptomatic coronary artery disease (n=301). Invasive strategy (coronary angiography followed by CABG or PCI) vs. Optimised medical strategy was evaluated on Critical clinical events (p=<0.0001).

synapsesocial.com/papers/6ac47b49fd49799cb2204214 https://doi.org/10.3390/cardiovascmed6010003

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Ältere Patienten mit symptomatischer koronarer Herzkrankheit: Ist die interventionelle Behandlung eine reelle Option?

Study Design

PICO

Main Result

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Abstract

Discussion

Cite This Study

Ältere Patienten mit symptomatischer koronarer Herzkrankheit: Ist die interventionelle Behandlung eine reelle Option?

Study Design

PICO

Main Result

Ask about this paper

Abstract

Discussion

Cite This Study

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