Shows protection against diabetic kidney disease in db/db mice, indicating the need for new treatments.
mice. These results indicate that, in type 2 diabetes, DKD is associated with reduced renal and cardiac superoxide levels and that MTP-131 protects against DKD and preserves physiological superoxide levels, possibly by regulating cardiolipin remodeling.
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Miyamoto et al. (2020) studied this question.
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