Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 1, 2026

Diffusion-weighted imaging and dynamic susceptibility contrast-enhanced perfusion-weighted imaging of the non-enhancing peritumoural region predict overall survival in glioblastoma.

View Full Paper
Ask AI
Bookmark
Share

Authors

MXM XiongFujian Medical UniversityJKJ KangFujian Medical UniversityFYF YuFujian Medical University

Discussion

Loading...

Member takes

Overview

Randomized trial investigates imaging parameters that predict survival outcomes in glioblastoma, indicating their potential as biomarkers.

Key Points

  • This research aims to assess the predictive value of DWI and DSC-PWI parameters for overall survival in patients with IDH-wildtype glioblastoma.
  • Retrospective collection of adult patients with IDH-wildtype glioblastoma undergoing gross total resection.
  • Categorization into short-term survivors and long-term survivors based on overall survival time.
  • Analysis of imaging parameters using t-tests, ROC curves, and Spearman correlation.
  • Short-term survivors showed significantly lower rADCmin-p (1.35 ± 0.27) compared to long-term survivors (1.80 ± 0.32; P < 0.001).
  • Short-term survivors had higher rCBVmax-p (4.46 ± 2.34) than long-term survivors (2.17 ± 0.85; P < 0.001).
  • The combined imaging model achieved an AUC of 0.909 for predicting overall survival.

Cite This Study

Xiong et al. (2026) studied this question.

synapsesocial.com/papers/6a44ad585cd2549c8bc42de0https://doi.org/10.1016/j.crad.2026.107359
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diffusion-weighted imaging and dynamic susceptibility contrast-enhanced perfusion-weighted imaging of the non-enhancing peritumoural region predict overall survival in glioblastoma2026
  2. 2Multiparametric MRI with DWI, SWI, and DSC-PWI for preoperative prediction of Ki-67, IDH, and ATRX in adult-type diffuse gliomas2026
  3. 3The impact of diffusion and perfusion-weighted imaging on glioma grading2024 · 1 citations
  4. 4Multiparametric MRI for differential diagnosis of primary central nervous system lymphoma and atypical glioblastoma: an analysis incorporating DWI, DCE-MRI, and contrast agent preload DSC-PWI2025 · 3 citations
  5. 5IMG-01. Higher Cerebral Metabolic Rate of Oxygen derived from Dynamic Susceptibility Contrast MRI is an Independent Predictor of Poor Survival in IDH-Wildtype Glioblastoma2025