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June 29, 2026HLA

Extended Characterisation of the Coding Sequence of the HLA‐DQB1*02:97 Allele by Next‐ and Third‐Generation Sequencing

Romain Clément Marion Raguenault Diana Ratiarison Isabelle Jollet

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Key Points

The research aims to detail the differences between the HLA-DQB1*02:97 and HLA-DQB1*02:02:01:01 alleles.
Utilized next-generation and third-generation sequencing techniques
Analyzed coding sequences in detail
Focused on single nucleotide variations in exon 4
Identified a single nucleotide substitution at codon 224 in the HLA-DQB1*02:97 allele
Differentiated HLA-DQB1*02:97 allele from its counterpart HLA-DQB1*02:02:01:01

Implication

Characterizes HLA-DQB1*02:97 allele by examining its genetic differences, indicating significant insights into immune genetics.

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Cite This Study

Clément et al. (2026) studied this question.

synapsesocial.com/papers/6a44add75cd2549c8bc43368 https://doi.org/10.1111/tan.70832

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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