Key result
Young adults (<45 years) presenting with STEMI had a significantly lower prevalence of pulmonary edema and cardiogenic shock compared to older patients (3% vs. 10%, OR 4.43).
Why the study?
The study was conducted to investigate the clinical profiles and outcomes of young adults presenting with STEMI.
What are the clinical profiles and outcomes of young adults (<45 years) presenting with STEMI compared to older adults?
Observational (n=402)
No
What are the clinical profiles and outcomes of young adults (<45 years) presenting with STEMI compared to older adults?
Odds Ratio: 4.43 (95% CI 1.75–10.94)
Absolute Event Rate: 3% vs 10%
p-value: p=0.002
Young adults with STEMI have favorable outcomes, but high rates of smoking and undiagnosed dyslipidemia highlight the need for targeted screening and prevention programs.
Young STEMI patients show favorable outcomes with smoking and undiagnosed dyslipidemia as key risks; leaves open targeted screening pending prospective studies.
OBJECTIVES: To investigate the clinical profiles and outcomes of young adults presenting with ST-segment elevation myocardial infarction (STEMI). METHODS: We retrospectively reviewed King Saud Medical City, Riyadh, Saudi Arabia, registry between January 2016 and November 2017 for all patients younger than 45 years old who were admitted with STEMI. We compared this study population to a control group of patients aged 45 years and older who were enrolled in the same period. RESULTS: =0.03). CONCLUSION: ST-segment elevation myocardial infarction in young patients has a favorable outcome. Smoking and dyslipidemia are the main risk factors for STEMI in young individuals. The majority of young patients with dyslipidemia were not aware of their pre-existing condition. Our findings recommend local adaptation and implementation of screening programs for dyslipidemia in the young and the reinforcement of smoking prevention programs.
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Sakr et al. (2021) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=402). Young age (<45 years) vs. Older age (≥45 years) was evaluated on Pulmonary edema and cardiogenic shock on presentation (OR 4.43, 95% CI 1.750-10.94, p=0.002). Young adults (<45 years) presenting with STEMI had a significantly lower prevalence of pulmonary edema and cardiogenic shock compared to older patients (3% vs. 10%, OR 4.43).
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