Key result
Proactive management using HFMS data cuts 90-day HF rehospitalizations by ~38% versus blinded control.
Why the study?
There is an unmet need for early detection of heart failure decompensation to enable remote management and avoid hospitalization.
Does proactive management using data from a wearable Heart Failure Monitoring System (HFMS) reduce heart failure rehospitalization in patients recently discharged for a heart failure event?
Population
522 patients discharged within 10 days post-hospitalization with a HF event in the prior 6 months
Comparison
Proactive wearable HF sensor data to direct therapy vs blinded sensor data with usual care
Design
Multicenter concurrent control study with an open-label intervention arm
Follow-up
90 days
Authors
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Supports proactive HF monitoring post-discharge; hypothesis-generating and requires randomized confirmation before practice change.
RCT (n=522)
Open-label
Yes
Does proactive management using data from a wearable Heart Failure Monitoring System (HFMS) reduce heart failure rehospitalization in patients recently discharged for a heart failure event?
Hazard Ratio: 0.62
p-value: p=0.03
Proactive management using data from a wearable heart failure sensor significantly reduces 90-day heart failure rehospitalization in recently discharged patients.
Boehmer et al. (2024) conducted an RCT in Heart Failure (n=522). Heart Failure Monitoring System (HFMS) vs. Usual care (blinded HFMS) was evaluated on Time to first HF hospitalization (HR 0.62, p=0.03). Proactive management using Heart Failure Monitoring System data reduced the rate of 90-day heart failure rehospitalization by 38% compared to a blinded control arm (HR 0.62; P=0.03).
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