Why the study?
Patients with congenital heart disease suffer from neurodevelopmental abnormalities, prompting a review of recent studies on outcomes, risk factors, biomarkers, and therapeutic interventions.
Population
Patients with congenital heart disease
Design
Review
Key result
Recent literature highlights the role of genetics, modifiable perioperative risk factors, and neurotoxic therapies in determining neurologic prognosis in patients with congenital heart disease.
Authors
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May guide risk stratification in congenital heart disease; leaves open validation of biomarkers and interventions.
This review emphasizes the need for biomarkers and psychosocial interventions to address neurodevelopmental abnormalities and improve quality of life in patients with congenital heart disease.
White et al. (2019) conducted a review in Congenital heart disease. Recent literature highlights the role of genetics, modifiable perioperative risk factors, and neurotoxic therapies in determining neurologic prognosis in patients with congenital heart disease.