Key result
Body mass index exhibited a U-shaped relationship with cardiovascular disease-specific mortality among adults with hypertension, where both underweight and obese individuals faced higher mortality risks compared to normal-weight patients.
Why the study?
How is body mass index associated with cardiovascular disease-specific mortality in adults with hypertension?
Cohort (n=212,394)
Yes
How is body mass index associated with cardiovascular disease-specific mortality in adults with hypertension?
Answers are grounded in this paper and cite their sources.
A U-shaped relationship exists between BMI and CVD mortality in hypertensive adults, suggesting an 'obesity paradox' where overweight and obesity may be protective against CVD death in older individuals.
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Hu et al. (2021) conducted a cohort in Hypertension (n=212,394). Body mass index (BMI) vs. Normal weight (BMI 18.5-24.9 kg/m2) was evaluated on Cardiovascular disease (CVD)-specific mortality (HR 1.37, 95% CI 1.22-1.53, p=<0.001). Body mass index exhibited a U-shaped relationship with cardiovascular disease-specific mortality among adults with hypertension, where both underweight and obese individuals faced higher mortality risks compared to normal-weight patients.
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