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This research aims to analyze the lipid and fatty acid composition of milk from nine mammalian species for nutritional assessment.

July 5, 2026npj Science of FoodOpen Access

Integrated lipidomics and fatty acid positional distribution for nutritional assessment of nine mammalian milks

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This research aims to analyze the lipid and fatty acid composition of milk from nine mammalian species for nutritional assessment.
Characterized lipid composition using liquid chromatography–tandem mass spectrometry.
Determined fatty acid distribution using solid-phase extraction and selective hydrolysis methods.
Compared milk from nine species including cow, buffalo, yak, and human.
Ruminant milks showed high compositional similarity; distinct differences found with camel and monogastric milks.
Animal milks had higher triacylglycerols and phospholipids compared to human milk; lower free fatty acids were noted.
Donkey milk identified as the closest analog to human milk in lipid composition according to Bray–Curtis analysis.

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Randomized trial characterizes lipidomics and fatty acid distribution in mammalian milks, highlighting nutritional differences.

Chen et al. (2026) studied this question.

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