Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 5, 2026DiagnosticsOpen Access

MEIS1::NCOA2 Fusion Sarcoma of the Bartholin Gland: A Case Report and Review of the Literature

View Full Paper
Ask AI
Bookmark
Share

Authors

PDPauline DumonceauxLSLoréane SimsAFAline François

Discussion

Loading...

Member takes

Overview

Case report reveals a new MEIS1::NCOA2 fusion sarcoma, suggesting RNA sequencing's role in diagnosis.

Key Points

  • The aim is to describe a rare case of MEIS1::NCOA2 fusion sarcoma and review existing literature.
  • Literature review conducted on PubMed for molecularly confirmed MEIS1::NCOA1/2 fusion sarcomas.
  • Clinicopathological, molecular, treatment, and outcome data were extracted for analysis.
  • Case report of a 38-year-old woman with a Bartholin gland mass and associated treatment details.
  • The tumor revealed the MEIS1::NCOA2 fusion transcript and CTNNB1 mutation.
  • Local recurrence was documented, prompting surgical re-excision and adjuvant radiotherapy.
  • First reported case exploring radiotherapy with curative intent for MEIS1::NCOA2 fusion sarcoma.

Cite This Study

Dumonceaux et al. (2026) studied this question.

synapsesocial.com/papers/6a49f70df5d1d45b28801285https://doi.org/10.3390/diagnostics16132098
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A locally aggressive pelvic MEIS1::NCOA1 fusion sarcoma in a young adult female: a case report and review of the literature2025 · 3 citations
  2. 2Spindle Cell Sarcoma of the Uterine Corpus With Adipose Metaplasia: Expanding the Morphologic Spectrum of Neoplasms With MEIS1-NCOA2 Gene Fusion2021 · 19 citations
  3. 3Low-grade undifferentiated sarcoma with MEIS1::NCOA2-rearrangement primary to the lung: a case report2024 · 8 citations
  4. 4Aggressive High-grade Uterine Sarcoma Harboring MEIS1-NCOA2 Fusion and Amplification of Multiple 12q13-15 Genes: A Case Report With Morphologic, Immunohistochemical, and Molecular Analysis2023 · 23 citations
  5. 5Primary Fallopian Tube Mullerian Adenosarcoma With Sarcomatous Overgrowth and a Previously Unreported MEIS1-NCOA2 Gene Fusion2021 · 10 citations