Key result
InterTAK score with prior coronary history clarifies retrospective diagnosis of recurrent Takotsubo syndrome.
Why the study?
Recurrence of Takotsubo syndrome is the most significant challenge in the long-term follow-up of patients with Takotsubo syndrome.
Case Report (n=1)
A thorough analysis of previous coronary events using the InterTAK Diagnostic Score can facilitate the reassessment of prior diagnoses and identify underdiagnosed recurrent Takotsubo syndrome.
May aid retrospective recognition of recurrent Takotsubo in complex ACS cases; leaves open prospective validation of InterTAK-guided diagnosis.
Recurrence of Takotsubo syndrome (TS) is the most significant challenge in the long-term follow-up of patients with TS. We present the case of a 40-year-old woman with a history of two acute coronary syndromes and myocarditis who was hospitalized in our clinic due to Takotsubo syndrome. Left ventriculography demonstrated the rare mid-ventricular variant of Takotsubo syndrome. Based on a carefully obtained medical history, it was established that all previous coronary events, as well as the current TS episode, had been preceded by psychological stress. Following an additional review of the patient’s medical records and application of the InterTAK score, we concluded that the previous incidents may have been episodes of TS and that the patient had now experienced her fourth episode of Takotsubo syndrome.
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Zalewska-Adamiec et al. (2026) conducted a case report in Takotsubo syndrome (n=1). Retrospective diagnosis using InterTAK Diagnostic Score was evaluated. A thorough analysis of previous coronary events combined with the InterTAK Diagnostic Score facilitated the retrospective diagnosis of recurrent Takotsubo syndrome in a 40-year-old woman.
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