Key result
The age-related increase in arterial stiffness was augmented according to hypertension severity, with the highest age tertile showing an odds ratio for increased baPWV of 18.5 in hypertensive men and 25.1 in hypertensive women.
Why the study?
Does the severity of hypertension augment the age-related increase in arterial stiffness?
Population
5,312 subjects with no atherosclerotic risk factors other than high blood pressure, selected from two…
Design
Cross-sectional
Authors
Loading...
May support stricter BP targets in hypertension; hypothesis-generating from observational data, needs RCTs.
Cross-Sectional (n=5,312)
Yes
Does the severity of hypertension augment the age-related increase in arterial stiffness?
Odds Ratio: 18.5 (95% CI 9.6–35.3)
p-value: p=<0.01
The age-related increase in arterial stiffness is progressively augmented by the severity of hypertension, supporting strict blood pressure control even in the elderly.
Tomiyama et al. (2004) conducted a cross-sectional in Hypertension (n=5,312). Severity of hypertension vs. Normal blood pressure was evaluated on Risk of having increased brachial-ankle pulse wave velocity (baPWV) in the highest age tertile compared to the lowest age tertile (OR 18.5, 95% CI 9.6-35.3, p=<0.01). The age-related increase in arterial stiffness was augmented according to hypertension severity, with the highest age tertile showing an odds ratio for increased baPWV of 18.5 in hypertensive men and 25.1 in hypertensive women.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: