Key result
Heart failure was associated with an increased risk of dementia (HR 1.84; 95% CI 1.35-2.51) and Alzheimer disease (HR 1.80; 95% CI 1.25-2.61) in older adults.
Why the study?
Does heart failure increase the risk of dementia and Alzheimer disease in older adults?
Cohort (n=1,301)
Does heart failure increase the risk of dementia and Alzheimer disease in older adults?
Hazard Ratio: 1.84 (95% CI 1.35–2.51)
Heart failure is significantly associated with an increased risk of developing dementia and Alzheimer disease in older adults, an effect that may be partially mitigated by antihypertensive therapy.
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Heart failure was associated with higher dementia risk in older adults; leaves open whether antihypertensives attenuate this link.
Qiu et al. (2006) conducted a cohort in Dementia and Alzheimer disease (n=1,301). Heart failure vs. No heart failure was evaluated on dementia (HR 1.84, 95% CI 1.35-2.51). Heart failure was associated with an increased risk of dementia (HR 1.84; 95% CI 1.35-2.51) and Alzheimer disease (HR 1.80; 95% CI 1.25-2.61) in older adults.
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