Key result
Heart failure was associated with a significantly increased risk of all-cause dementia (OR/RR 1.28; 95% CI 1.15-1.43; P<0.001).
Why the study?
Outcomes regarding cognitive impairment in HF differ due to fragmented evidence and small sample sizes, prompting a systematic review of the association between HF and dementia.
Does heart failure increase the risk of dementia?
Comparison
Heart failure vs no heart failure
Design
Systematic review and meta-analysis
Authors
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May support cognitive screening in HF patients; leaves open causality and need for prospective trials.
Meta-Analysis
Does heart failure increase the risk of dementia?
Odds Ratio: 1.28 (95% CI 1.15–1.43)
p-value: p=<0.001
Heart failure is associated with a significantly increased risk of developing all-cause dementia, highlighting the importance of cognitive monitoring in this patient population.
Li et al. (2020) conducted a meta-analysis in Heart failure. Heart failure vs. No heart failure was evaluated on All-cause dementia (OR/RR 1.28, 95% CI 1.15 to 1.43, p=<0.001). Heart failure was associated with a significantly increased risk of all-cause dementia (OR/RR 1.28; 95% CI 1.15-1.43; P<0.001).
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