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July 8, 2026MicrobiologyOpenOpen Access

Detection of OXA‐23 Among Carbapenem‐Resistant Acinetobacter baumannii Isolated From Intensive Care Units of a Tertiary Care Hospital in Pakistan

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Authors

HWHafsa WaseemIUIhsan UllahSAShahzad Ahmad

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Overview

Cross-sectional study detects bla OXA-23 in carbapenem-resistant Acinetobacter baumannii, suggesting urgent infection control actions.

Key Points

  • The research aims to identify the presence of the bla OXA-23 gene in carbapenem-resistant Acinetobacter baumannii isolates from ICU patients.
  • Cross-sectional study conducted over one year in an intensive care unit.
  • Carbapenem-resistant isolates were confirmed phenotypically, then genotypically verified using PCR for bla OXA-23.
  • Phenotypic confirmation involved detecting bla OXA-51 and PCR mapping for ISAba1 insertion.
  • 100% of 52 isolates tested positive for the bla OXA-23 gene with upstream ISAba1.
  • Sequence type ST19 was the most prevalent, found in 59.6% of isolates, followed by ST2 (26.9%) and ST1 (13.4%).
  • Findings indicate a pressing need for improved infection control and surveillance in ICU settings.

Cite This Study

Waseem et al. (2026) studied this question.

synapsesocial.com/papers/6a4de93fd2ea289ef62838b6https://doi.org/10.1002/mbo3.70364
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