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July 8, 2026Environmental ToxicologyOpen Access

Cytogenotoxic and Molecular Assessment of Pyrethrins on Non‐Target Allium cepa Roots

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Authors

YUYudum Yeltekin UğurRIRahsan Ilikci-SagkanRLRecep Liman

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Overview

Randomized trial assesses cytogenotoxic impacts of pyrethrins on Allium cepa, indicating potential harm to non-target plants.

Key Points

  • This research aims to evaluate the cytogenotoxic and apoptotic effects of pyrethrins on Allium cepa root cells.
  • Evaluated root growth inhibition, Allium ana-telophase, comet assay, flow cytometry, and RAPD-PCR assays.
  • Measured root length and assessed mitotic index (MI) and chromosomal aberrations in response to pyrethrins.
  • Conducted flow cytometric analysis to determine apoptotic cell populations and genomic stability.
  • Root length decreased significantly from 2.84 ± 0.45 cm at low doses to 0.13 ± 0.09 cm at high concentrations.
  • Increased MI abnormalities and chromosomal aberrations were observed, with a marked dose-response relationship.
  • RAPD-PCR revealed diminished genomic template stability percentage in A. cepa after pyrethrin exposure, suggesting genotoxic effects.

Cite This Study

Uğur et al. (2026) studied this question.

synapsesocial.com/papers/6a4de9e4d2ea289ef6283ee5https://doi.org/10.1002/tox.70149
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