Key result
Ultrasound time-harmonic elastography detected significantly higher age-adjusted aortic shear-wave speed in hypertensive patients compared to healthy participants (0.24 vs 0.07 m/s; P<0.001).
Why the study?
To investigate ultrasound time-harmonic elastography for quantifying aortic stiffness in vivo in the context of aging and arterial hypertension.
Does ultrasound time-harmonic elastography detect increased aortic stiffness in patients with long-standing hypertension compared to healthy participants?
Comparison
Participants with long-standing hypertension vs healthy participants
Design
Prospective observational study
Follow-up
6 months
Authors
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Supports noninvasive aortic stiffness assessment in hypertension; leaves open its diagnostic and prognostic utility.
Observational (n=74)
Does ultrasound time-harmonic elastography detect increased aortic stiffness in patients with long-standing hypertension compared to healthy participants?
Absolute Event Rate: 0.24% vs 0.07%
p-value: p=<0.001
Ultrasound time-harmonic elastography is a reproducible method that can quantify aortic wall stiffness in vivo and accurately distinguish patients with arterial hypertension from healthy individuals.
Schaafs et al. (2019) conducted an observational in Arterial hypertension (n=74). Arterial hypertension vs. Healthy participants was evaluated on Age-adjusted shear-wave speed (SWS) (p=<0.001). Ultrasound time-harmonic elastography detected significantly higher age-adjusted aortic shear-wave speed in hypertensive patients compared to healthy participants (0.24 vs 0.07 m/s; P<0.001).
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