Physical Activity Measured With Implanted Devices Predicts Patient Outcome in Chronic Heart Failure
Key result
Higher early physical activity measured by implanted devices predicted a lower risk of death or heart failure hospitalization (HR 0.96 per 10 min/day increase; 95% CI 0.94-0.98; P=0.0002).
Why the study?
Does early physical activity measured by implanted devices predict death or HF hospitalization in patients with chronic heart failure?
Population
781 analyzed patients with chronic heart failure and an implantable cardioverter defibrillator without or…
Comparison
Early physical activity measured continuously by… vs Lower levels of physical activity.
Design
Cohort
Follow-up
15±7 months
Authors
Discussion
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Member takes
Implication
Device-tracked activity may refine prognostic assessment in HF; leaves open whether increasing activity improves outcomes.
Study Design
Type
Cohort (n=781)
Structured PICO
Does early physical activity measured by implanted devices predict death or HF hospitalization in patients with chronic heart failure?
P
Population
781 patients (mean age 65, 15% female) with chronic heart failure and an implantable cardioverter defibrillator, followed for a mean of 15 months.
E
Exposure
Early physical activity (average daily activity over the earliest 30-day study period) measured continuously by implanted devices (single-axis accelerometer).
C
Comparator
Lower levels of physical activity (evaluated as a continuous variable, per 10 minutes/day).
O
Outcome
Time to death or HF-related hospital admission.composite
Main Result
Hazard Ratio: 0.96 (95% CI 0.94–0.98)
p-value: p=0.0002
Early physical activity measured by implanted devices independently predicts mortality and heart failure hospitalization in patients with chronic heart failure.
Cite This Study
Conraads et al. (2014) conducted a cohort in Chronic heart failure (n=781). Early physical activity (measured via implanted device) vs. Lower physical activity was evaluated on Time to death or HF-related hospital admission (HR 0.96, 95% CI 0.94-0.98, p=0.0002). Higher early physical activity measured by implanted devices predicted a lower risk of death or heart failure hospitalization (HR 0.96 per 10 min/day increase; 95% CI 0.94-0.98; P=0.0002).