Key result
High-temporal velocity-encoded MRI showed good correlation with Color M-mode echocardiography for assessing left ventricular inflow propagation velocity.
Why the study?
Does high-temporal velocity-encoded MRI accurately assess left ventricular inflow propagation velocity compared to Color M-mode echocardiography in patients with ischemic heart failure and healthy volunteers?
Cross-Sectional (n=65)
Does high-temporal velocity-encoded MRI accurately assess left ventricular inflow propagation velocity compared to Color M-mode echocardiography in patients with ischemic heart failure and healthy volunteers?
High-temporal velocity-encoded MRI provides a reliable alternative to echocardiography for assessing left ventricular inflow propagation velocity and identifying impaired relaxation.
Answers are grounded in this paper and cite their sources.
VE-MRI may enable alternative Vp assessment in heart failure; leaves open validation and clinical adoption.
PURPOSE: To develop an alternative method for Vp-assessment using high-temporal velocity-encoded magnetic resonance imaging (VE-MRI). Left ventricular (LV) inflow propagation velocity (Vp) is considered a useful parameter in the complex assessment of LV diastolic function and is measured by Color M-mode echocardiography. MATERIALS AND METHODS: A total of 43 patients diagnosed with ischemic heart failure (61 ± 11 years) and 22 healthy volunteers (29 ± 13 years) underwent Color M-mode echocardiography and VE-MRI to assess the inflow velocity through the mitral valve (mean interexamination time 14 days). Temporal resolution of VE-MRI was 10.8-11.8 msec. Local LV inflow velocity was sampled along a 4-cm line starting from the tip of the mitral leaflets and for consecutive sample points the point-in-time was assessed when local velocity exceeded 30 cm/s. From the position-time relation, Vp was calculated by both the difference quotient (Vp-MRI-DQ) as well as from linear regression (Vp-MRI-LR). RESULTS: Good correlation was found between Vp-echo and both Vp-MRI-DQ (r = 0.83, P < 0.001) and Vp-MRI-LR (r = 0.84, P < 0.001). Vp-MRI showed a significant but small underestimation as compared to Vp measured by echocardiography (Vp-MRI-DQ: 5.5 ± 16.2 cm/s, P = 0.008; Vp-MRI-LR: 9.9 ± 15.2 cm/s, P < 0.001). Applying age-related cutoff values for Vp to identify LV impaired relaxation, kappa-agreement with echocardiography was 0.72 (P < 0.001) for Vp-MRI-DQ and 0.69 (P < 0.001) for Vp-MRI-LR. CONCLUSION: High temporal VE-MRI represents a novel approach to assess Vp, showing good correlation with Color M-mode echocardiography. In healthy subjects and patients with ischemic heart failure, this new method demonstrated good agreement with echocardiography to identify LV impaired relaxation.
No takes yet. Share an insight, caveat, or question.
Calkoen et al. (2015) conducted a cross-sectional in Ischemic heart failure (n=65). High-temporal velocity-encoded magnetic resonance imaging (VE-MRI) vs. Color M-mode echocardiography was evaluated on Left ventricular inflow propagation velocity (Vp) (r = 0.83, p=<0.001). High-temporal velocity-encoded MRI showed good correlation with Color M-mode echocardiography for assessing left ventricular inflow propagation velocity.
Synapse has enriched 10 related papers. Consider them for comparative context: