Key result
In patients with LBBB, high-risk dipyridamole myocardial perfusion scans were associated with a significantly lower overall survival rate compared to low-risk scans (79.2% vs 98.1%, p=0.034).
Why the study?
Does dipyridamole technetium-99m-sestamibi myocardial perfusion imaging predict hard cardiac events in patients with preexisting left bundle-branch block?
Population
76 patients with preexisting left bundle-branch block with or without chest pain, mean age 53 +/- 10 years
Comparison
High-risk scans on technetium-99m-sestamibi… vs Low-risk scans on technetium-99m-sestamibi…
Design
Cohort
Follow-up
24 +/- 8 months
Authors
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May support perfusion imaging for risk stratification in LBBB; leaves open whether it improves outcomes in trials.
Cohort (n=76)
Does dipyridamole technetium-99m-sestamibi myocardial perfusion imaging predict hard cardiac events in patients with preexisting left bundle-branch block?
Absolute Event Rate: 79.2% vs 98.1%
p-value: p=0.034
Dipyridamole technetium-99m-sestamibi myocardial perfusion imaging provides significant prognostic value for predicting cardiac death and myocardial infarction in patients with left bundle-branch block.
Usmani et al. (2009) conducted a cohort in Preexisting left bundle-branch block (LBBB) with or without chest pain (n=76). High-risk myocardial perfusion scan vs. Low-risk myocardial perfusion scan was evaluated on Overall survival rate (p=0.034). In patients with LBBB, high-risk dipyridamole myocardial perfusion scans were associated with a significantly lower overall survival rate compared to low-risk scans (79.2% vs 98.1%, p=0.034).
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