Key result
Direct insertion of a floppy pigtail guidewire significantly reduced time to steerable guide catheter insertion compared to the traditional technique (17 vs 30 minutes; P=0.001).
Why the study?
Does direct insertion of a floppy pigtail guidewire reduce time to steerable guide insertion compared to traditional stiff wire insertion in patients undergoing the MitraClip procedure?
Observational (n=39)
Does direct insertion of a floppy pigtail guidewire reduce time to steerable guide insertion compared to traditional stiff wire insertion in patients undergoing the MitraClip procedure?
Using a floppy pigtail guidewire for left atrial access during MitraClip procedures safely reduces the time required for steerable guide insertion compared to traditional stiff wire techniques.
Answers are grounded in this paper and cite their sources.
May expedite left atrial access in MitraClip; leaves open confirmation of safety and outcomes in randomized trials.
BACKGROUND: To assess whether a new floppy pigtail guidewire provides sufficient support for introduction of the 22F-steerable guide catheter (SG) into the left atrium and is less time-consuming during the MitraClip(®) -procedure without necessity of probing and inserting a stiff wire into the pulmonary vein. METHODS: In group 1, traditional probing of the left upper pulmonary vein and insertion of a standard stiff wire was used. In group 2, direct insertion of the floppy pigtail guidewire directly after transseptal puncture was used. RESULTS: Patients in group 1 (n = 18) and group 2 (n = 21) did not differ significantly with respect to mitral regurgitation severity (3.2 ± 0.4 vs 3.2 ± 0.4; P = 0.814) and etiology (functional 78% vs 71%, P = 0.651). Comparing both methods, a significant reduction in time-to-SG was observed in group 2 versus group 1 (17 ± 7 minutes vs 30 ± 11 minutes; P = 0.001). The rate of crossing failures was 0% with use of the floppy pigtail guidewire as well as with the traditional technique. No complications were observed with use of the floppy pigtail guidewire. CONCLUSIONS: Utilization of a thin, floppy pigtail guidewire for left atrium access is safe and markedly accelerates insertion of the SG for the MitraClip(®) -procedure without crossing failures of the atrial septum.
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Büchner et al. (2015) conducted an observational in Mitral regurgitation (n=39). Direct insertion of a floppy pigtail guidewire vs. Traditional probing with a standard stiff wire was evaluated on Time to steerable guide catheter insertion (time-to-SG) (p=0.001). Direct insertion of a floppy pigtail guidewire significantly reduced time to steerable guide catheter insertion compared to the traditional technique (17 vs 30 minutes; P=0.001).
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