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July 11, 2026International Journal of Surgery OpenOpen Access

Clinical characteristics and prognostic analysis of patients with primary intestinal non-Hodgkin lymphoma treated by comprehensive strategies – a retrospective cohort study from a single center in Eastern China

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Authors

HXHao XiaXPXiao-Ping Pei

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Overview

Retrospective cohort study investigates survival outcomes in patients with primary intestinal non-Hodgkin lymphoma, highlighting key prognostic factors.

Key Points

  • To analyze clinical characteristics and treatment strategies of patients with primary intestinal non-Hodgkin lymphoma and their impact on prognosis.
  • Retrospective study of 37 patients with primary intestinal non-Hodgkin lymphoma diagnosed from September 2012 to February 2022.
  • Collected clinical data and follow-up times; assessed lactic dehydrogenase as a prognostic marker using ROC curves.
  • Evaluated overall survival rates and identified risk factors through univariate and multivariate analyses.
  • 1-year and 5-year overall survival rates were 64.9% and 38.4%, respectively (95% CI: 49.6%–80.2%, 21.9%–54.9%).
  • LDH levels ≥ 246 U/L indicated a worse prognosis (HR = 3.365, P = 0.015).
  • Combined surgery and chemotherapy improved survival outcomes significantly (P = 0.042).

Cite This Study

Xia et al. (2026) studied this question.

synapsesocial.com/papers/6a51ddbfc18d7f28ca50012chttps://doi.org/10.1097/io9.0000000000000384
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