Key result
In patients with heart disease, a knee extensor muscle strength cutoff value of 0.46 kgf/kg was identified as a predictor for achieving a peak oxygen uptake corresponding to 5 metabolic equivalents.
Why the study?
Mortality increases when peak oxygen uptake is under 5 metabolic equivalents, and this study aimed to determine the knee extensor muscle strength corresponding to that threshold.
Cross-Sectional (n=45)
No
Effect estimate: AUC 0.86
A knee extensor muscle strength cutoff of 0.46 kgf/kg can be used to predict a peak oxygen uptake of 5 metabolic equivalents in patients with heart disease undergoing cardiac rehabilitation.
May guide strength targets in cardiac rehab; hypothesis-generating and requires prospective validation before practice change.
[Purpose] The mortality rate increases when peak oxygen uptake is less than 5 metabolic equivalents, and peak oxygen uptake correlates with knee extensor muscle strength. This study aimed to determine the knee extensor muscle strength at peak oxygen uptake corresponding to 5 metabolic equivalents. [Participants and Methods] We enrolled 45 consecutive patients (29 males and 16 females; average age, 63.6 ± 13.7 years) with heart disease receiving outpatient rehabilitation with us. We performed cardiopulmonary exercise testing with a bicycle ergometer to measure peak oxygen uptake. We investigated the relationship between peak oxygen uptake and isometric knee extensor muscle strength divided by the body weight (kgf/kg). The cutoff value for knee extensor muscle strength with peak oxygen uptake corresponding to 5 metabolic equivalents was calculated. [Results] Knee extensor muscle strength was significantly positively associated with peak oxygen uptake. The cutoff value for knee extensor muscle strength at peak oxygen uptake corresponding to 5 metabolic equivalents was 0.46 kgf/kg. [Conclusion] In this study, the cutoff value for knee extensor muscle strength for achieving peak oxygen uptake corresponding to 5 metabolic equivalents in patients with heart disease was 0.46kgf/kg.
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Yokote et al. (2020) conducted a cross-sectional in Heart disease (n=45). Knee extensor muscle strength was evaluated on Cutoff value of knee extensor muscle strength for peak oxygen uptake at 5 metabolic equivalents (AUC 0.86). In patients with heart disease, a knee extensor muscle strength cutoff value of 0.46 kgf/kg was identified as a predictor for achieving a peak oxygen uptake corresponding to 5 metabolic equivalents.
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