Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 2020Integrative Cancer TherapiesOpen Access

Home-Based Physical Activity in Patients With Breast Cancer: During and/or After Chemotherapy? Impact on Cardiorespiratory Fitness. A 3-Arm Randomized Controlled Trial (APAC)

View Full Paper
Ask AI
Bookmark
Share

Key result

Home-based adapted physical activity improved cardiorespiratory fitness in breast cancer patients, with no significant difference in VO2peak at 12 months regardless of program timing.

Why the study?

Physical activity is recommended in breast cancer care, but optimal modalities and timing regarding treatment remain unclear.

Does the timing of home-based adapted physical activity (during vs after chemotherapy) improve cardiorespiratory fitness in patients with breast cancer?

Population

94 patients with breast cancer

Comparison

6 months APA during adjuvant care vs 6 months after adjuvant care vs 12 months during and after care

Design

3-arm randomized controlled trial

Follow-up

12 months

Authors

FVF. VincentInsermÉDÉlise DelucheUniversité de LimogesJBJoëlle BonisUniversité de Limoges

Discussion

Loading...

Member takes

Overview

Home-based activity boosts fitness in breast cancer patients regardless of timing; reinforces exercise integration during and after chemotherapy.

Study Design

Type

RCT (n=94)

Randomization

3-arm

Structured PICO

Does the timing of home-based adapted physical activity (during vs after chemotherapy) improve cardiorespiratory fitness in patients with breast cancer?

P
Population
94 patients with breast cancer randomized to a home-based adapted physical activity program during, after, or during and after adjuvant care, followed for 12 months.
I
Intervention
Home-based adapted physical activity (APA) combining 1 resistance and 2 aerobic sessions per week for 6 months during adjuvant care (Group A) or 6 months after adjuvant care (Group B)
C
Comparator
12 months of APA during and after specific care (Group C)
O
Outcome
Peak oxygen consumption (VO2peak) at 12 monthssurrogate

Home-based adapted physical activity improves cardiorespiratory fitness in breast cancer patients, with no significant difference in 12-month outcomes based on whether the program is initiated during or after chemotherapy.

Cite This Study

Vincent et al. (2020) conducted an RCT in Breast cancer (n=94). Home-based adapted physical activity (APA) vs. Different timings of APA (during, after, or both) was evaluated on Peak oxygen consumption (VO2peak) at 12 months. Home-based adapted physical activity improved cardiorespiratory fitness in breast cancer patients, with no significant difference in VO2peak at 12 months regardless of program timing.

synapsesocial.com/papers/6a557e8d104eb60be6085369https://doi.org/10.1177/1534735420969818
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Randomized Controlled Trial of Exercise Training in Postmenopausal Breast Cancer Survivors: Cardiopulmonary and Quality of Life Outcomes2003 · 762 citations
  2. 2Physical activity patterns associated with cardiorespiratory fitness and reduced mortality: the Aerobics Center Longitudinal Study.1998 · 182 citations
  3. 3Effects of supervised exercise training on cardiopulmonary function and fatigue in breast cancer survivors during and after treatment2007 · 154 citations
  4. 4A Prospective Study of Cardiorespiratory Fitness and Breast Cancer Mortality2009 · 124 citations
  5. 5A Comparison of Physical Activity Preferences Among Breast, Prostate, and Colorectal Cancer Survivors in Nova Scotia, Canada2014 · 23 citations