Key result
A newly developed mathematical model of mouse atrial cardiomyocytes produced channel block simulation results that quantitatively agreed with existent experimental data.
Population
Newly developed mathematical model of mouse atrial cardiomyocytes
Comparison
Channel block simulations
Design
Mathematical simulation study
Authors
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Mouse atrial model aids ion channel research; leaves open human arrhythmia translation without validation.
A newly developed mathematical model of mouse atrial cardiomyocytes provides a tool for investigating ion channel mechanisms of atrial electrical activity and arrhythmogenesis.
Zhang et al. (2020) studied Atrial arrhythmogenesis. Mathematical model of mouse atrial cardiomyocytes vs. Existent experimental data was evaluated on Channel currents in atrial action potential. A newly developed mathematical model of mouse atrial cardiomyocytes produced channel block simulation results that quantitatively agreed with existent experimental data.
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