Why the study?
The study aimed to investigate d-dimer for predicting venous thromboembolism events during puerperium and to identify other associated risk factors.
Does d-dimer level within postpartum 24 hours predict venous thromboembolism during puerperium in women who gave birth after 28 weeks of gestation?
Population
16 127 women who gave birth after 28 weeks of gestation
Comparison
Biomarkers and risk factors evaluated for association with VTE
Design
Prospective observational cohort study
Key result
A postpartum d-dimer level ≥3.70 mg/L was independently associated with venous thromboembolism during puerperium (OR 7.573; 95% CI 2.699-21.247).
Authors
Loading...
May support postpartum VTE risk stratification; leaves open prospective validation before practice change.
Cohort (n=16,127)
No
Does d-dimer level within postpartum 24 hours predict venous thromboembolism during puerperium in women who gave birth after 28 weeks of gestation?
Odds Ratio: 7.573 (95% CI 2.699–21.247)
A d-dimer level ≥3.70 mg/L within 24 hours postpartum is a strong independent predictor of venous thromboembolism during the puerperium.
Hu et al. (2020) conducted a cohort in Venous thromboembolism in puerperium (n=16,127). d-dimer ≥3.70 mg/L vs. d-dimer <3.70 mg/L was evaluated on Venous thromboembolism (VTE) (OR 7.573, 95% CI 2.699-21.247). A postpartum d-dimer level ≥3.70 mg/L was independently associated with venous thromboembolism during puerperium (OR 7.573; 95% CI 2.699-21.247).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: