Key result
In patients with newly diagnosed type 2 diabetes, left atrial diameter (OR 1.16; 95% CI 1.07-1.25; P<0.001) and interventricular septal thickness were independently associated with hypertension.
Why the study?
Whether type 2 diabetes mellitus is independently associated with structural heart abnormalities is controversial due to associated confounders.
Is newly diagnosed type 2 diabetes mellitus associated with structural heart abnormalities on echocardiography compared to controls?
Population
128 newly diagnosed T2DM cases (62 hypertensive, 66 non-hypertensive) and controls
Comparison
Newly diagnosed T2DM patients vs controls, and hypertensive vs non-hypertensive T2DM
Design
Retrospective study
Authors
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May identify early structural risks in new T2DM; hypothesis-generating and should not yet change practice.
Case-Control
No
Is newly diagnosed type 2 diabetes mellitus associated with structural heart abnormalities on echocardiography compared to controls?
Odds Ratio: 1.16 (95% CI 1.07–1.25)
p-value: p=<0.001
Patients with newly diagnosed type 2 diabetes mellitus already exhibit structural heart abnormalities on echocardiography, with left atrial diameter and interventricular septal thickness independently associated with concomitant hypertension.
Zhao et al. (2020) conducted a case-control in Newly diagnosed Type 2 Diabetes Mellitus. Type 2 Diabetes Mellitus and Hypertension vs. Controls without T2DM / T2DM patients without hypertension was evaluated on Independent association of left atrial diameter (LAd) with hypertension in patients with T2DM (OR 1.16, 95% CI 1.07-1.25, p=<0.001). In patients with newly diagnosed type 2 diabetes, left atrial diameter (OR 1.16; 95% CI 1.07-1.25; P<0.001) and interventricular septal thickness were independently associated with hypertension.
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