Key result
Fatty liver disease was independently associated with higher average heart rate, greater cardiac remodelling, and lower ventricular and atrial volumes (p < 0.001).
Why the study?
Growing evidence links fatty liver disease (FLD) with cardiac dysfunction and remodelling, but its independent contribution required investigation.
Is fatty liver disease independently associated with cardiac dysfunction and remodelling?
Observational (n=18,848)
Is fatty liver disease independently associated with cardiac dysfunction and remodelling?
p-value: p=<0.001
Fatty liver disease is an independent predictor of higher heart rate and early adverse cardiac remodeling, highlighting a potential structural mechanism for increased cardiovascular risk in these patients.
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May support cardiac monitoring in fatty liver disease; leaves open causal role and need for longitudinal trials.
Jamialahmadi et al. (2023) conducted an observational in Fatty liver disease (n=18,848). Fatty liver disease vs. Without fatty liver disease was evaluated on Cardiac dysfunction and remodelling (heart rate, eccentricity ratio, remodelling index, and cardiac volumes) (p=<0.001). Fatty liver disease was independently associated with higher average heart rate, greater cardiac remodelling, and lower ventricular and atrial volumes (p < 0.001).
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