Key result
Clinically documented fatigue was not independently associated with overall mortality (HR 1.00) in newly diagnosed heart failure patients after adjusting for physiologic confounders.
Why the study?
Does clinically documented fatigue predict mortality in newly diagnosed heart failure patients?
Population
12,285 newly diagnosed heart failure patients receiving health care services through the Geisinger Health…
Comparison
Clinically documented fatigue vs No clinically documented fatigue
Design
Cohort
Follow-up
average 4.8 years
Authors
Loading...
Fatigue should not guide mortality prognostication in new HF; leaves open its role in symptom management and requires prospective validation.
Cohort (n=12,285)
Yes
Does clinically documented fatigue predict mortality in newly diagnosed heart failure patients?
Hazard Ratio: 1 (95% CI 0.94–1.06)
p-value: p=0.89
Clinically documented fatigue is common in newly diagnosed HF patients and is strongly associated with depression and other symptoms, but it does not independently predict long-term mortality.
Brent A. Williams (2017) conducted a cohort in Heart failure (n=12,285). Clinically documented fatigue vs. No fatigue was evaluated on Overall all-cause mortality (HR 1.00, 95% CI 0.94-1.06, p=0.89). Clinically documented fatigue was not independently associated with overall mortality (HR 1.00) in newly diagnosed heart failure patients after adjusting for physiologic confounders.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: