Key result
Low household income was associated with higher interleukin-6 concentrations across all race/ethnic groups, with a 1-SD lower income linked to a 9% increase (95% CI 7-11) among whites.
Why the study?
Is low socioeconomic position associated with higher levels of inflammation markers (CRP and IL-6) across different race/ethnic groups?
Cross-Sectional (n=6,814)
Is low socioeconomic position associated with higher levels of inflammation markers (CRP and IL-6) across different race/ethnic groups?
Effect estimate: 9% difference (95% CI 7-11)
Lower socioeconomic position is associated with higher systemic inflammation across multiple racial/ethnic groups, a relationship that appears to be largely mediated by adiposity.
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Supports targeting adiposity to address socioeconomic inflammation disparities; hypothesis-generating for prospective equity trials.
Ranjit et al. (2007) conducted a cross-sectional in Cardiovascular risk (n=6,814). Low socioeconomic position (household income and education) vs. Higher socioeconomic position was evaluated on Interleukin-6 and C-reactive protein concentrations (9% difference, 95% CI 7-11). Low household income was associated with higher interleukin-6 concentrations across all race/ethnic groups, with a 1-SD lower income linked to a 9% increase (95% CI 7-11) among whites.
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