Association of Inflammatory Markers With Socioeconomic Status
Key result
Low socioeconomic status was associated with significantly elevated levels of inflammatory markers compared to high socioeconomic status, largely explained by behavioral factors.
Why the study?
Is low socioeconomic status associated with elevated serum levels of inflammatory markers in well-functioning older adults?
Population
3044 well-functioning older men and women, aged 70-79 from Pittsburgh, Pennsylvania and Memphis, Tennessee…
Comparison
Low socioeconomic status as indicated by… vs High socioeconomic status (SES)
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May support behavioral interventions in low-SES older adults; leaves open causality and needs prospective confirmation.
Study Design
Type
Cross-Sectional (n=3,044)
Multicenter
Yes
Structured PICO
Is low socioeconomic status associated with elevated serum levels of inflammatory markers in well-functioning older adults?
P
Population
3,044 well-functioning older adults aged 70-79 from the Health, Aging and Body Composition study.
E
Exposure
Low socioeconomic status (SES) as indicated by education, income, and ownership of financial assets
C
Comparator
High socioeconomic status (SES)
O
Outcome
Serum levels of inflammatory markers (interleukin-6, C-reactive protein, and tumor necrosis factor-alpha)surrogate
Low socioeconomic status in older adults is associated with elevated systemic inflammation, a relationship substantially mediated by modifiable behavioral factors such as smoking, drinking, and obesity.
Cite This Study
Koster et al. (2006) conducted a cross-sectional in well-functioning older adults (n=3,044). Low socioeconomic status vs. High socioeconomic status was evaluated on Serum levels of interleukin-6, C-reactive protein, and tumor necrosis factor-alpha. Low socioeconomic status was associated with significantly elevated levels of inflammatory markers compared to high socioeconomic status, largely explained by behavioral factors.