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September 5, 2018Medicine & Science in Sports & Exercise

Type 1 Muscle Fiber Hypertrophy after Blood Flow–restricted Training in Powerlifters

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Key result

Blood flow-restricted resistance exercise induced selective increases in type I myofiber area (12% vs 0%, P<0.01) and myonuclear number compared to conventional training in powerlifters.

Why the study?

Does blood flow-restricted resistance exercise improve muscle hypertrophy and strength compared to conventional training in powerlifters?

Population

17 national level powerlifters, mean age 25 ± 6 years, 15 men

Comparison

Blood flow-restricted resistance exercise… vs Conventional training group performing front…

Design

RCT, randomly assigned

Follow-up

6.5 weeks

Authors

TBThomas BjørnsenMWMathias WernbomAKAlexander Kirketeig

Discussion

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Overview

BFRRE may offer low-load option for type I hypertrophy in powerlifters; extends fiber-specific BFR evidence to competitive athletes.

Study Design

Type

RCT (n=17)

Randomization

randomly assigned

Structured PICO

Does blood flow-restricted resistance exercise improve muscle hypertrophy and strength compared to conventional training in powerlifters?

P
Population
17 national level powerlifters (mean age 25, 12% female) were randomized to blood flow-restricted resistance exercise or conventional training for 6.5 weeks.
I
Intervention
Blood flow-restricted resistance exercise (BFRRE) consisting of two blocks (weeks 1 and 3) of five BFRRE front squat sessions within a 6.5-wk training period (four sets at ~30% of 1RM)
C
Comparator
Conventional training group performing front squats at 60%-85% of 1RM
O
Outcome
Myofiber areas (MFA), number of myonuclei and satellite cells (SC), muscle size and strengthsurrogate

Main Result

Absolute Event Rate: 12% vs 0%

p-value: p=< 0.01

Low-load blood flow-restricted resistance exercise in powerlifters increases quadriceps cross-sectional area and preferentially hypertrophies type 1 muscle fibers compared to conventional training.

Cite This Study

Bjørnsen et al. (2018) conducted an RCT in Healthy (national level powerlifters) (n=17). Blood flow-restricted resistance exercise (BFRRE) vs. Conventional training at 60%-85% of 1RM was evaluated on Increase in type I myofiber area (MFA) (p=< 0.01). Blood flow-restricted resistance exercise induced selective increases in type I myofiber area (12% vs 0%, P<0.01) and myonuclear number compared to conventional training in powerlifters.

synapsesocial.com/papers/6a5d5a5bd50e1fe7bb039ce8https://doi.org/10.1249/mss.0000000000001775
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Proliferation of myogenic stem cells in human skeletal muscle in response to low‐load resistance training with blood flow restriction2012 · 269 citations
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