Key result
Administration of azithromycin in a 60-year-old female resulted in concurrent severe QT prolongation (QTc 640ms) and profound deep T-wave inversions that improved upon discontinuation.
Why the study?
Macrolide-induced QT prolongation is well documented, but limited reports exist of medication-induced deep T-wave inversions.
Case Report (n=1)
No
Azithromycin can induce concurrent deep T-wave inversions and QT prolongation, an ECG pattern that requires comprehensive workup to rule out acute ischemia or cerebral hemorrhage.
No takes yet. Share an insight, caveat, or question.
Azithromycin may cause deep TWI with QT prolongation; this Level 5 case leaves open incidence and monitoring needs.
Wasilewski et al. (2022) conducted a case report in Community-acquired pneumonia (n=1). Azithromycin was evaluated on Development of QT prolongation and deep T-wave inversions. Administration of azithromycin in a 60-year-old female resulted in concurrent severe QT prolongation (QTc 640ms) and profound deep T-wave inversions that improved upon discontinuation.
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