Why the study?
What factors are linked to azithromycin-induced QTc interval prolongation and torsade de pointes?
What factors are linked to azithromycin-induced QTc interval prolongation and torsade de pointes?
Elderly women with heart disease and multiple risk factors are at particularly high risk for azithromycin-related QTc interval prolongation and torsade de pointes.
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Assess cumulative QTc risk factors before azithromycin use regardless of dose; confirms multiple risks predominate over dose in prolongation.
Hancox et al. (2013) studied this question.
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