Why the study?
Does the addition of oral azithromycin to long-term amiodarone therapy cause QT prolongation?
Does the addition of oral azithromycin to long-term amiodarone therapy cause QT prolongation?
The combination of azithromycin and amiodarone can cause marked QT prolongation and increased QT dispersion, warranting caution when co-administering these drugs.
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Supports caution with azithromycin-amiodarone co-administration; leaves open interaction frequency and need for controlled QT studies.
Samarendra et al. (2001) studied this question.
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